Tag Archive: leaky gut

D. Fragilis Is Reportedly Gone

One thing that we have learned on this journey is that CB has a sensitive immune system. He doesn’t get sick often, knock on wood, but his system is sensitive to random infections, bugs, and immune suppressors. During the last few years, he has tested positive for yeast infections, anal strep, d. fragilis, selective IgA deficiency, multiple vitamin deficiencies (despite eating healthy and a variety of foods), food sensitivities, and allergies. OK, some of these are common, but I don’t believe anal strep and d. fragilis are all that common.

The latest culprit is d. fragilis, dientamoeba fragilis. D. fragilis is a parasite that lives in the large intestine. It is controversial as to whether it is pathogenic. If you do a quick search on the web, you will see many anecdotal reports stating that it can cause IBS type symptoms, decrease the body’s ability to absorb iron, and can be very hard to anihilate. You can read more about dientamoeba fragilis at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862407/. (more…)

Parasites Strike Again

For me and for most of the moms I know, after we take in the fact that our child has special needs, we set off on a journey to find the root cause of our child’s challenges and sometimes illnesses. Even when we think we have an answer, it is not the final answer. Things are always in flux and we are always learning something new. Information posted a few years ago may already be disproven or at the least improved upon. Even though we know CB has a genetic difference, genetic variance, genetic mutation, whatever you want to call it, we know that he exhibits a myriad of symptoms that may or may not be 100% related to this genetic variance. He could exhibit some behaviors because the genetic variance makes his body more susceptible to other infections, illnesses, or other difficulties.

Our latest work up results included blood, urine, and stool.  We did this as we were considering seeing a pediatric gastrointologist. This pediatric gastrointologist wanted an extensive work up including blood, urine, and stool before he will see your child. His visits are also 100% out of pocket and if he has to do a scope, a good portion is not covered by insurance. Since it was time to do CB’s usual blood work, we added in the extra tests. The good news is that we do not feel we need to move forward with a visit to the pediatric gastrointologist based off the results of the work up. (sigh of relief). The concerning news is that CB’s iron is still low and his IgA levels have fallen even lower. His wbc count is low but nothing else on the CBC. His zinc and vitamin D look fine but we supplement those. The other interesting finding is that his stool still contains d. fragilis. This is the same parasite identified in his stool from another lab almost a year ago. We treated the parasite with humaworm. Actually, the entire family took humaworm. We felt his symptoms had improved afterwards. Since we did not test again, I don’t know if it actually cured it and he was reinfected or it never fully cured it.  (more…)

Why all this talk about gut?

I realize that it may seem strange to dedicate a decent amount of this blog to my son’s gut issues. So I thought it might be helpful to provide some more resources and context regarding why I have taken this route and spent so much time mentioning my son’s gut over the past year. All the therapies are crucial and I would never suggest just focusing on your child’s gut if they have neurological problems; however, I think it is crucial to consider and explore if your child also has digestive issues, as well. For CB, he had chronic loose stools since he was a baby and through blood work,it was identified that he had numerous vitamin deficiencies, selective IgA deficiency, and borderline iron anemia despite eating balanced, healthy meals. I knew I wanted to help CB’s issues in the most natural way possible. Through diet changes and supplements, the selective IgA deficiency down-graded to low IgA so it no longer classified as an autoimmune condition, all vitamin and iron levels were within the normal range, and his stools were normal most of the time. I’ve noted throughout my blog the specifics but some only took a couple of months to change while others took about a year. In this same time frame, CB has made tremendous jumps with his speech, social interactions, core strength, attention, coordination, appropriate play, and become potty-trained. I believe that my son’s blood work came back with so many issues b/c he had a leaky gut.

What is a Leaky Gut?

The practitioners at SCD Lifestyle provide a good explanation:

“The term Leaky Gut Syndrome is used to describe the condition of “Hyperpermeable Intestines,” a fancy medical term that means the intestinal lining has became more porous, with more holes developing that are larger in size and the screening out process is no longer functioning properly. The fallout results in larger, undigested food molecules and other “bad stuff” (yeast, toxins, and all other forms of waste) that your body normally doesn’t allow through, to flow freely into your bloodstream.

So now that we have the general essentially meaningless definition out of the way let’s find out what is really going on…

The intestinal lining is the first mechanism of defense for our immune system. The outer layers of intestinal cells (epithelial) are connected by structures called tight junctions. At the tips of these cells are the microvilli, which absorb properly digested nutrients and transport them through the epithelial cell and into the bloodstream. During the normal digestion process the tight junctions stay closed forcing all molecules to effectively be screened and only pass into the blood stream through the mucosa cells (think of them like bouncers at the front of a classy bar). For reasons we will discuss later, these tight junctions can become “open” or permeable allowing un-screened molecules to flow directly into the bloodstream (think of it like a fish net with very small holes).”

By making the dietary changes, this has allowed my son’s intestinal wall to heal or mostly heal. What I don’t know at this point is 1) Can CB eat gluten again? 2) If so, do we need to limit it? 3) Or will he need to remain gluten-free his whole life? 4) Will the soy allergy go away? 5) By healing the gut, can it remain healed? 6) Even though we are not seeing any issues with slowly introducing dairy, are there internal problems forming that we can’t see? (more…)

Positive Progress based off Latest Blood Workup

Yay, CB’s progress is continually being reflected in the blood workup CB partakes in every 4-6 months or so. The highlights are that all his iron levels are within normal range, his IgA levels are still rising, his CMP was completely normal, and his homocysteine levels are getting close to the low-end of normal. What does all this mean? His diet and supplements are working!! We implemented the modified diet and many of the supplements based off CB’s original blood workup test results from April last year. You can read more about where CB started from blood workup-wise in my blog at Current diet and supplements.

The number of tests performed with CB’s blood workup has grown since his first one a year and a half ago. On the latest workup, the following tests were performed:

  • CBC w/autodiff w/platelets
  • CMP
  • Ferritin
  • Iron and IBC
  • Immunoglob IgA
  • Immunoglob IgG
  • Immunoglob IgM
  • Immunoglob IgE
  • Folic Acid?
  • Magnesium
  • Lipid Panel
  • TSH Free to Reflex T4
  • Vitamin B12
  • Vitamin D, 25
  • Vitamin A
  • Vitamin E
  • Vitamin K1
  • Methylmalonic Acid
  • Zinc, serum
  • Homocysteine

(more…)

Allergy Report & First Food Reintroduction

CB is 4 years old …

Life is going well here in our little household. Olem and I are both thinking positively and just enjoying life. It is easy to see how CB’s behavior can be quite linked to our moods and reactions. CB is having a great week at school. I guess the aggression last week was either tied to the return to school after our trip and/or the reintroduction of fish oil after a 5 day break due to our little vacation. CB is still a bit off. His therapists mentioned that he did a good job and performed what was asked but that he struggled more and seemed more foggy-headed than he has been lately. When things like this happen, we immediately start looking into what is going on with him outside of therapy to see if there is a logical or easily-identifiable reason. CB is experiencing some seasonal allergies which may be contributing to these struggles. We now think the rash on his bottom is potentially linked to his seasonal allergies. We also found out he has to wear non-elastic underwear. The elastic irritates his skin.

We got 90% of his allergy report back and were pleasantly surprised. He only showed an allergy to mold (indoor and outdoor) and a borderline potential for a peanut allergy. Olem had allergy shots as a kid and was allergic to a long list of things so we really expected to see similar results for CB. CB’s nutritionist had recommended back in January that we hold off performing an allergy test b/c she felt the report would show a lot of false positives since his nutrition report showed several vitamin deficiencies and the selective IGA deficiency. I posted more about that at my Current Diet and Supplements post. Since his latest nutrition report showed that his body is in a much improved state, we decided to move forward with the allergy report.

We reintroduced plain whole milk yogurt (first casein protein introduction) yesterday into CB’s diet. He had a small amount yesterday afternoon and a small amount this afternoon. So far, he hasn’t shown any noticeable reaction. We really hope he can have yogurt again. We think CB for sure had, and potentially still has, leaky gut issues. Since his body is no longer reporting malabsorption issues, we thought it would be a good time to start reintroducing foods. We know the modified diet has helped, but we don’t know 100% why or what specific components have helped his body. Our plan is to reintroduce foods slowly, monitor CB’s body, emotional, and physical response, and have another nutrition report performed in 6 months. Hopefully, we will see some changes in one form or another that tell us when his body is having problems with a specific type of food. By performing the nutrition report in 6 months, we will be able to see if any vitamin deficiencies or malabsorption issues have returned.

Positive progress: CB stayed dry all night and urinated in the toilet on his own first thing in the morning. His sleep was very interrupted last night b/c of his younger brother. There is the chance he didn’t get to sleep as deeply and was able to control it better. Still, it is a great step for CB! Also, CB’s vestibular system is integrating more fully. He requested more types of swings during OT and at the pediatric therapy play gym and seems way more comfortable.